AfHNS guidelines for evaluation of a thyroid nodule / mass


  • Wayne’s Index
  • After addressing possible thyrotoxicosis, U/S may assist to differentiate a single hyper-vascular (potentially hyperfunctional) nodule vs.  diffusely hypervascular goiter (Graves disease)
  • Other than with a rapidly growing thyroid mass, biopsy of a thyroid nodule is typically not urgent, and referral to a better resourced center for FNAC is recommended
  • If not possible, reliance is placed on clinical and U/S findings to risk-stratify using the Thyroid Imaging Reporting and Data System (TI-RADS)
  • Patients with high risk clinical and sonographic features are advised to have surgery with histological review of the thyroid specimen

Return to Thyroid nodule Evaluation Resource Appropriate Guidelines

Index: Clinical Practice Guidelines for Thyroid