Evaluation of Glottic Cancer: Key points

  • Histological diagnosis is essential
  • Squamous cell carcinoma (SCC) is most common
  • Exclude inflammatory causes e.g. TB
  • Principal treatment options are surgery +/- adjuvant radiation therapy; or (chemo)radiation
  • Objectives of preoperative evaluation
    • Confirm diagnosis
    • Describe the precise location of the cancer
    • Stage the primary cancer and the neck and exclude distant metastases
    • Decide whether to offer curative or palliative treatment
  • Patient evaluation
    • Fitness for surgery / chemoradiation
    • Ability to cope with aspiration if partial laryngectomy, chemoradiation considered
    • Ability to complete surgery and postoperative radiation therapy, or chemoradiation
    • Ability to deal with the long-term consequences of treatment e.g. dysphagia, aspiration, tracheostomy, hypothyroidism, voice disturbance/aphonia
  • Surgery
    • Plan appropriate surgery
    • Avoid inappropriate surgery
    • Avoid surgery beyond the scope of the surgeon e.g. complex salvage surgery

Index: Clinical Practice Guidelines for Glottic Cancer

Resource Appropriate Glottic Cancer Guideline Scenarios